Table 3 Univariate analysis
From: Children's vomiting following posterior fossa surgery: A retrospective study
Variable | POV by 120 Hours Odds Ratio (95% CI) | Early (≤ 24 hours) vs. Late POV1 Odds Ratio (95% CI) |
|---|---|---|
1. Site | Â | Â |
   Stollery Children's Hospital | 1.00 | 1.00 |
   Hospital for Sick Children | 1.74 (0.92–3.29) | 1.71 (0.73–4.03) |
2. Child Characteristics | Â | Â |
   Age |  |  |
0 to <4 years | 1.00 | 1.00 |
4 to <6 years | 1.10 (0.48–2.49) | 0.26 (0.11–0.64)** |
7 to <12 years | 0.90 (0.42–1.92) | 0.30 (0.13–0.69)** |
12 to <17 years | 0.54 (0.24–1.23) | 0.41 (0.16–1.08) |
   Female Gender | 0.79 (0.45–1.38) | 1.39 (0.74– 2.62) |
   Required Surgery |  |  |
Brain Tumour | 1.00 | 1.00 |
Chiari I Malformation | 2.32 (1.17–4.60)* | 0.60 (0.30–1.19) |
Other | 0.39 (0.13–1.13) | 4.86 (0.90–26.30) |
3. Presenting Symptom | Â | Â |
   Presenting with Vomiting | 0.95(0.55–1.67) | 1.09 (0.58–2.05) |
4. Intraoperative Care | Â | Â |
   Administration of Ondansetron | 1.78 (1.00–3.15) | 0.74 (0.39–1.38) |
   Administration of Dexamethasone | 0.65 (0.37–1.15) | 1.62 (0.86–3.05) |
   Length of surgery | 1.00 (0.98–1.01) | 1.00 (0.98–1.01) |
   Use of Desflurane | 1.32 (0.66–2.64) | 0.34 (0.14–0.83)* |
5. Test of Interaction: Ondansetron and Dexamethasone | Adjusted Odds Ratio (95% CI) | Adjusted Odds Ratio (95% CI) |
Step 1 | Â | Â |
   Intraoperative ondansetron | 1.92 (1.07–3.45)* | 1.75 (1.91–3.35) |
   Intraoperative dexamethasone | 0.59 (0.33–1.06) | 0.66 (0.34–1.26) |
Step 2 | Â | Â |
   Intraoperative ondansetron | 1.43 (0.58–3.53) | 0.37 (0.13–1.03) |
   Intraoperative dexamethasone | 0.49 (0.23–1.02) | 1.10 (0.45–2.67) |
   Dexamethasone X ondansetron | 1.63 (0.50–5.30) | 2.86 (0.73–11.13) |