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Table 5 Multivariable analysis: Early vs. late POV (POV in the first 24 hours vs. after 24 hours to 120 hours)1

From: Children's vomiting following posterior fossa surgery: A retrospective study

Model Number

4

3

2

1

Variable

Adjusted Odds Ratio

(95% CI)

Adjusted Odds Ratio

(95% CI)

Adjusted Odds Ratio

(95% CI)

Odds Ratio

(95% CI)

1. Site

    

   Stollery Children's Hospital

1.00

1.00

1.00

1.00

   Hospital for Sick Children

0.72

(0.22–2.19)

1.80

(0.72–4.52)

1.80

(0.72–4.50)

1.71

(0.72–4.03)

2. Child Characteristics

    

   Age in quartiles%

    

0 to <4 years

1.00

1.00

1.00

 

4 to <7 years

0.30

(0.11–0.79) *

0.31

(0.12–0.79)*

0.31

(0.12–0.78)*

 

7 to <12 years

0.31

(0.13–0.79)*

0.32

(0.13–0.77)*

0.32

(0.13–0.76)*

 

12 to <17 years

0.50

(0.17–1.48)

0.47

(0.17–1.30)

0.47

(0.17–1.29)

 

   Female Gender

1.90

(0.93–3.91)

1.62

(0.81–3.21)

1.62

(0.82–3.21)

 

   Required Surgery

    

Brain Tumour

1.00

1.00

1.00

 

Chiari I Malformation

0.64

(0.22–1.88)

0.64

(0.20–1.38)

0.57

(0.27–1.20)

 

Other

2.82

(0.39–20.70)

2.63

(0.40–16.19)

2.70

(0.45–16.14)

 

3. Presenting Symptom

    

   Presenting with Vomiting

0.71

(0.26–1.84)

0.89

(0.36–2.17)

  

4. Intraoperative Care

    

   Administration of Ondansetron

0.85

(0.40–1.80)

   

   Administration of Dexamethasone

2.02

(0.87–4.68)

   

   Length of surgery

1.00

(0.98–1.02)

   

   Use of Desflurane

0.23

(0.07–0.73)*

   
  1. 1. Early vomiting coded as 0 and late vomiting coded as 1, n = 181.
  2. *p < .05 **p < .01
  3. α Change ≥ 15% in a statistically significant variable or ≥ 15% making a variable statistically significant CI = Confidence Interval