Table 3 Treatment effect on time to healing adjusted for explanatory co-variates

Centre¹

Grouping 1

< 0.01

1.0

< 0.01

1.0

Grouping 2

< 0.01

2.2 (1.6-3.1)

< 0.01

1.8 (1.2-2.6)

Grouping 3

< 0.01

2.8 (2.0-4.0)

< 0.01

2.3 (1.6-3.4)

Grouping 4

< 0.01

2.6 (1.8-3.7)

< 0.01

2.5 (1.7-3.7)

Grouping 5

< 0.01

4.2 (3.2-5.6)

< 0.01

3.7 (2.7-5.0)

Gender²

Male

-

1.0

-

1.0

Female

0.34

1.1 (.90-1.4)

0.26

1.1 (.91-1.4)

Age

Decades

< 0.01

1.1 (1.1-1.2)

0.04

1.1 (1.0-1.1)

Living situation

Alone

-

1.0

-

1.0

With others

0.09

1.2 (.97-1.5)

0.08

1.2 (.98-1.5)

Co-morbidities

None

< 0.01

1.0

n.s.

1-2

0.06

1.3 (1.0-1.7)

> 3

< 0.01

2.2 (1.5-1.3)

Pain on Admission

Yes

-

1.0

n.s

No

0.02

1.5 (1.1-2.1)

Mobility

Fully mobile

-

1.0

n.s

Walks with assistance/immobile

0.02

1.4 (1.1-1.7)

Ankle flexion

Full flexion

-

1.0

n.s

Impaired/no flexion

0.10

1.3 (.96-1.6)

Edema

Yes

-

1.0

N/A

No

0.86

1.0 (.77-1.4)

ABPI

< 0.01

5.7 (3.0-10.9)

n.s

Previous Ulcer

Yes

-

1.0

N/A

No

0.64

1.0 (.86-1.3)

Ulcer duration

≤ 12 weeks

< 0.01

1.8 (1.5-2.2)

n.s

> 12 weeks

-

1.0

Ulcer size

≤ 2.5 cm

< 0.01

2.7 (2.1-3.5)

< 0.01

2.1 (1.5-2.7)

> 2.5 to ≤ 10 cm

< 0.01

1.6 (1.2-2.0)

< 0.01

1.5 (1.1-2.0)

> 10 cm

< 0.01

1.0

< 0.01

1.0

Allocated Bandage

Four layer

-

1.0

0.77

1.0

Short stretch

0.99

1.0 (.82-1.2)

1.0 (.84-1.3)