Skip to main content

Advertisement

Table 3 Univariate analysis

From: Children's vomiting following posterior fossa surgery: A retrospective study

Variable POV by 120 Hours
Odds Ratio (95% CI)
Early (≤ 24 hours) vs.
Late POV1
Odds Ratio (95% CI)
1. Site   
   Stollery Children's Hospital 1.00 1.00
   Hospital for Sick Children 1.74 (0.92–3.29) 1.71 (0.73–4.03)
2. Child Characteristics   
   Age   
0 to <4 years 1.00 1.00
4 to <6 years 1.10 (0.48–2.49) 0.26 (0.11–0.64)**
7 to <12 years 0.90 (0.42–1.92) 0.30 (0.13–0.69)**
12 to <17 years 0.54 (0.24–1.23) 0.41 (0.16–1.08)
   Female Gender 0.79 (0.45–1.38) 1.39 (0.74– 2.62)
   Required Surgery   
Brain Tumour 1.00 1.00
Chiari I Malformation 2.32 (1.17–4.60)* 0.60 (0.30–1.19)
Other 0.39 (0.13–1.13) 4.86 (0.90–26.30)
3. Presenting Symptom   
   Presenting with Vomiting 0.95(0.55–1.67) 1.09 (0.58–2.05)
4. Intraoperative Care   
   Administration of Ondansetron 1.78 (1.00–3.15) 0.74 (0.39–1.38)
   Administration of Dexamethasone 0.65 (0.37–1.15) 1.62 (0.86–3.05)
   Length of surgery 1.00 (0.98–1.01) 1.00 (0.98–1.01)
   Use of Desflurane 1.32 (0.66–2.64) 0.34 (0.14–0.83)*
5. Test of Interaction: Ondansetron and
Dexamethasone
Adjusted Odds Ratio
(95% CI)
Adjusted Odds Ratio
(95% CI)
Step 1   
   Intraoperative ondansetron 1.92 (1.07–3.45)* 1.75 (1.91–3.35)
   Intraoperative dexamethasone 0.59 (0.33–1.06) 0.66 (0.34–1.26)
Step 2   
   Intraoperative ondansetron 1.43 (0.58–3.53) 0.37 (0.13–1.03)
   Intraoperative dexamethasone 0.49 (0.23–1.02) 1.10 (0.45–2.67)
   Dexamethasone X ondansetron 1.63 (0.50–5.30) 2.86 (0.73–11.13)
  1. 1. Early vomiting coded as 0 and late as 1, no POV counted as missing therefore n = 181.
  2. *p < .05
  3. **p < .01
  4. CI = Confidence Interval