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Table 4 Multivariable analysis: POV by 120 hours

From: Children's vomiting following posterior fossa surgery: A retrospective study

Model Number 5 4 3 2 1
Variable Adjusted Odds Ratio
(95% CI)
Adjusted Odds Ratio
(95% CI)
Adjusted Odds Ratio
(95% CI)
Adjusted Odds Ratio
(95% CI)
Odds Ratio
(95% CI)
1. Site      
   Stollery Children's Hospital 1.00 1.00 1.00 1.00 1.00
   Hospital for Sick Children 3.92
(1.45–10.58)*
4.25
(1.62–11.12)α**
1.78
(0.90–3.51)
1.78
(0.90–3.50)
1.74
(0.92–3.29)
2. Child Characteristics      
   Age in quartiles%      
0 to <4 years 1.00 1.00 1.00 1.00  
4 to <7 years 0.86
(0.35–2.14)
0.84
(0.34–2.06)
0.96
(0.41–2.27)
1.00
(0.43–2.35)
 
7 to <12 years 0.51
(0.21–1.22)
0.56
(0.24–1.31)
0.72
(0.32–1.61)
0.74
(0.33–1.64)
 
12 to <17 years 0.34
(0.13–0.88)*
0.33
(0.13–0.82)α*
0.48
(0.20–1.12)
0.47
(0.20–1.11)
 
   Female Gender 0.64
(0.34–2.14)
0.66
(0.35–1.21)
0.71
(0.39–1.27)
0.69
(0.39–1.25)
 
   Surgery      
Brain Tumour 1.00 1.00 1.00 1.00  
Chiari I Malformation 2.78
(1.03–7.50)*
2.43
(0.91–6.48)α
3.46
(1.48–8.10)α**
2.80
(1.37–5.71)**
 
Other 0.65
(0.31–1.35)
0.53
(0.14–1.99)
0.54
(0.17–1.79)
0.44
(0.15–1.35)
 
3. Presenting Symptoms      
   Presenting with Vomiting 1.75
(0.79–3.91)
1.63
(0.75–3.54)
1.40
(0.67–2.90)
  
4. Intraoperative Care      
   Administration of Ondansetron 3.47
(1.61–7.47)**
2.22
(1.14–4.33)*
   
   Administration of Dexamethasone 0.65
(0.31–1.35)
0.58
(0.28–1.19)
   
   Length of surgery 0.90
(.76–1.06)
0.91
(0.78–1.08)
   
   Use of Desflurane 14.08
(2.47–80.32)**
3.11
(1.13–8.62)*
   
5. Significant Interaction      
Use of Desflurane X Intraoperative
administration of ondansetron
0.10
(0.12–0.55)**
    
  1. *p < .05
  2. **p < .01
  3. α Change ≥ 15% in a statistically significant variable or ≥ 15% making a variable statistically significant
  4. CI = Confidence Interval