Table 4 Multivariable analysis: POV by 120 hours
From: Children's vomiting following posterior fossa surgery: A retrospective study
Model Number | 5 | 4 | 3 | 2 | 1 |
|---|---|---|---|---|---|
Variable | Adjusted Odds Ratio (95% CI) | Adjusted Odds Ratio (95% CI) | Adjusted Odds Ratio (95% CI) | Adjusted Odds Ratio (95% CI) | Odds Ratio (95% CI) |
1. Site | Â | Â | Â | Â | Â |
   Stollery Children's Hospital | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
   Hospital for Sick Children | 3.92 (1.45–10.58)* | 4.25 (1.62–11.12)α** | 1.78 (0.90–3.51) | 1.78 (0.90–3.50) | 1.74 (0.92–3.29) |
2. Child Characteristics | Â | Â | Â | Â | Â |
   Age in quartiles% |  |  |  |  |  |
0 to <4 years | 1.00 | 1.00 | 1.00 | 1.00 | Â |
4 to <7 years | 0.86 (0.35–2.14) | 0.84 (0.34–2.06) | 0.96 (0.41–2.27) | 1.00 (0.43–2.35) |  |
7 to <12 years | 0.51 (0.21–1.22) | 0.56 (0.24–1.31) | 0.72 (0.32–1.61) | 0.74 (0.33–1.64) |  |
12 to <17 years | 0.34 (0.13–0.88)* | 0.33 (0.13–0.82)α* | 0.48 (0.20–1.12) | 0.47 (0.20–1.11) |  |
   Female Gender | 0.64 (0.34–2.14) | 0.66 (0.35–1.21) | 0.71 (0.39–1.27) | 0.69 (0.39–1.25) |  |
   Surgery |  |  |  |  |  |
Brain Tumour | 1.00 | 1.00 | 1.00 | 1.00 | Â |
Chiari I Malformation | 2.78 (1.03–7.50)* | 2.43 (0.91–6.48)α | 3.46 (1.48–8.10)α** | 2.80 (1.37–5.71)** |  |
Other | 0.65 (0.31–1.35) | 0.53 (0.14–1.99) | 0.54 (0.17–1.79) | 0.44 (0.15–1.35) |  |
3. Presenting Symptoms | Â | Â | Â | Â | Â |
   Presenting with Vomiting | 1.75 (0.79–3.91) | 1.63 (0.75–3.54) | 1.40 (0.67–2.90) |  |  |
4. Intraoperative Care | Â | Â | Â | Â | Â |
   Administration of Ondansetron | 3.47 (1.61–7.47)** | 2.22 (1.14–4.33)* |  |  |  |
   Administration of Dexamethasone | 0.65 (0.31–1.35) | 0.58 (0.28–1.19) |  |  |  |
   Length of surgery | 0.90 (.76–1.06) | 0.91 (0.78–1.08) |  |  |  |
   Use of Desflurane | 14.08 (2.47–80.32)** | 3.11 (1.13–8.62)* |  |  |  |
5. Significant Interaction | Â | Â | Â | Â | Â |
Use of Desflurane X Intraoperative administration of ondansetron | 0.10 (0.12–0.55)** |  |  |  |  |