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Table 3 Comparison of variables inter- and intra-group before and after six months of intervention (n=114)

From: The impact of nurse-led nonpharmacological multidisciplinary holistic nursing care on fatigue patients receiving hemodialysis: a randomized, parallel-group, controlled trial

Indicators

Experimental group (n=60)e

 

Control group (n=54)f

 

P

Median, P25(P75)

 

Median, P25(P75)

 

TSAT

8.05,2.27(14.89)

 

2.04,0.77(2.86)

 

0.000

RPFS ae

2.26,1.45(3.44)

 

0.48,0.25(1.03)

 

0.000

Mental fatigue e

1.41,0.61(2.89)

 

0.54,0.20(1.08)

 

0.000

Muscular fatigue e

2.13,1.24(3.00)

 

0.75,0.22(1.16)

 

0.000

PTH (pg/ml)

22.64,-27.35(63.96)

 

8.38,-26.36(67.46)

 

0.653

CRP (mg/L)

1.83,-2.21(8.29)

 

1.30,-3.40(4.35)

 

0.211

ALB (g/L)e

6.15,1.11(8.32)

 

4.40,1.70(8.56)

 

0.643

Hb (g/L)

7.98,-1.99(27.96)

 

5.48,1.73(22.97)

 

0.734

Fe (umol/L)

3.17,-2.17(7.62)

 

0.74,-1.76(4.64)

 

0.184

Ca (mmol/L)

0.17,-0.05(0.45)

 

0.09,-0.10(0.28)

 

0.135

P (mmol/L)

0.31,-0.43(0.99)

 

-0.04,-0.32(0.27)

 

0.183

SF (ug/L)

25.34,-12.36(52.64)

 

10.63,-13.01(29.12)

 

0.289

Urea (mmol/L)

3.36,-0.06(11.74)

 

1.61,-3.44(5.93)

 

0.016

PQSI c e

5.00,0.85(7.00)

 

2.00,0.00(2.00)

 

0.008

Anxiety e

2.00,-1.00(3.00)

 

1.00,0.00(1.00)

 

0.616

Vitality on the SF-36 e

5.01,1.02(8.95)

 

1.00,1.00(4.20)

 

0.035

Depression e

2.50,0.00(6.25)

 

0.00,0.00(0.00)

 

0.000

PSSS b

6.06,2.78(6.04)

 

5.06,-16.08(21.05)

 

0.881

Extrafamilial support

2.12,-16.13(16.24)

 

2.16,0.09(2.06)

 

0.973

Intrafamilial support

4.11,2.05(4.08)

 

2.12,0.07(6.08)

 

0.343

Overall behavioural self-management d

17.50,5.00(18.25)

 

5.50,1.00(10.00)

 

0.000

Compliance with recommendations for liquid intake e

4.00,1.00(7.00)

 

1.00,0.00(3.20)

 

0.000

Compliance with recommendations for sodium and protein intake e

3.00,1.00(5.00)

 

1.00,0.00(3.00)

 

0.000

Compliance with recommendations for iron intake e

2.00,0.00(3.00)

 

0.00,0.00(0.00)

 

0.000

Self-monitoring of disease e

1.00,0.00(2.00)

 

1.00,0.00(1.00)

 

0.164

Protecting the internal fistula

0.00,0.00(2.00)

 

0.00,0.00(1.00)

 

0.409

Maintaining personal health e

1.00,0.00(1.00)

 

0.00, 0.00(1.00)

 

0.076

Developing interests and hobbies

0.00,0.00(1.00)

 

0.00, 0.00(0.00)

 

0.424

Developing good habits

0.00,0.00(1.00)

 

0.00,0.00(1.00)

 

0.337

Seeking knowledge

0.00, -1.00(2.00)

 

0.00, 0.00(1.00)

 

0.877

Compliance with medication regimen

0.00,0.00(0.00)

 

0.00, 0.00(0.00)

 

1.000

 

Yes, n (%)

No, n (%)

Yes, n (%)

No, n (%)

 

Complications*#

55(57.3)

5(27.8)

41(42.7)

13(72.2)

0.073

Pruritus*

50(53.2)

10(50.0)

44(46.8)

10(50.0)

0.909

Pain (whole body) *@

18(46.2)

42(56.0)

21(53.8)

33(44.0)

0.363

 

Normal

n(%)

General

n(%)

Normal

n(%)

General n(%)

 

Appetite*&

10(62.5)

40(59.7)

6(37.5)

27(40.3)

0.029

  1. Abbreviations: CRP C-reactive protein, PTH parathyroid hormone, Hb haemoglobin, ALB albumin, P phosphorus, Ca calcium; Fe ferritin, SF serum ferritin, TSAT serum transferrin saturation, RPFS Revised Piper Fatigue Scale; SF-36 36-Item Short-Form Health Survey; PSSS Perceived Social Support Scale; PSQI Pittsburgh Sleep Quality Index
  2. The continuous within-group variables are reported as the median ± interquartile range of difference values between pre- and post-intervention measurements; the categorical variables are expressed as frequencies after intervention
  3. a Total fatigue scores can range from 0 to 10, of which 0, 1–3, 4–6, and 7–10 indicate no symptoms, mild symptoms, moderate symptoms, and severe symptoms, respectively
  4. b Total support scores can range from 12 to 84, with higher scores indicating better perceived social support
  5. c Total scores can range from 0 to 21, with ≤ 7 points indicating normal sleep and > 7 points indicating a sleep disorder
  6. d Total scores can range from 25 to 100, with a higher score indicating better behavioural self-management
  7. e Comparison of pre- and post-intervention values in the experimental group, P=0.000
  8. f Comparison of pre- and post-intervention values in the control group, P>0.05
  9. *Data are reported as post-intervention values, and the two groups were compared using Pearson’s chi-square test
  10. # Comparison of pre- and post-intervention values in the experimental group by McNemar’s nonparametric test for related samples, P=0.000
  11. @ Comparison of pre- and post-intervention values in the experimental group by McNemar’s nonparametric test for related samples, P=0.014
  12. & McNemar-Bowker test of cross-tabulations pre- and post-intervention in the experimental group, P=0.000