Table 2 Results from generalized linear models for normally distributed repeated measures data for QoL- 30 variables including corresponding baseline value as covariate

Quality of Life

45.0 (38.5–51.4)

46.7 (38.9–54.6)

−1.7 (−11.9–8.4) p = 0.74

49.5 (43.2–55.9)

47.8 (40.2–55.5)

1.7 (−8.3–11.7) p = 0.74

66.2 (59.9–72.4)

58.6 (50.8–66.3)

7.6 (−2.4–17.6) p = 0.13

76.1 (69.9–82.4)

67.9 (60.2–75.7)

8.2 (−1.8–18.2) p = 0.11

Physical Function

69.2 (63.6–74.7)

68.6 (61.8–75.3)

0.6 (−8.2–9.4) p = 0.89

70.9 (65.4–76.4)

70.9 (64.3–77.4)

0.0 (−8.6–8.6) p = 1.00

82.7 (77.4–88.0)

78.9 (72.2–85.5)

3.8 (−4.7–12.3) p = 0.38

88.0 (82.6–93.4)

84.8 (78.2–91.5)

3.2 (−5.4–11.7) p = 0.47

Role Function

36.2 (26.6–45.8)

37.0 (25.4–48.7)

−0.9 (−16.0–14.3) p = 0.91

35.2 (25.7–44.8)

38.0 (26.6–49.4)

−2.7 (−17.6–12.2) p = 0.72

70.4 (61.1–79.6)

56.7 (45.1–68.2)

13.7 (−1.1–28.6) p = 0.070

81.2 (71.9–90.5)

75.3 (63.7–86.8)

5.9 (−8.9–20.8) p = 0.43

Emotional Function

72.5 (66.2–78.8)

64.0 (56.4–71.7)

8.4 (−1.5–18.4) p = 0.096

71.7 (65.4–77.9)

67.2 (59.7–74.7)

4.5 (−5.3–14.3) p = 0.37

76.3 (70.3–82.4)

68.1 (60.5–75.7)

8.2 (−1.5–17.9) p = 0.097

81.6 (75.5–87.7)

77.7 (70.1–85.3)

3.8 (−5.9–13.6) p = 0.44

Cognitive Function

72.5 (66.0–78.9)

65.7 (57.8–73.6)

6.7 (−3.6–17.0) p = 0.20

75.4 (69.0–81.7)

70.2 (62.5–77.9)

5.1 (−4.9–15.2) p = 0.31

83.7 (77.5–89.9)

79.0 (71.2–86.7)

4.7 (−5.3–14.7) p = 0.35

86.1 (79.9–92.3)

83.7 (76.0–91.5)

2.4 (−7.6–12.4) p = 0.64

Social Function

47.4 (39.1–55.8)

50.7 (40.6–60.9)

−3.3 (−16.4–9.9) p = 0.62

56.7 (48.4–64.9)

54.4 (44.5–64.2)

2.3 (−10.6–15.2) p = 0.73

77.1 (69.1–85.0)

67.9 (57.9–77.9)

9.2 (−3.6–22.0) p = 0.16

86.0 (78.0–94.1)

75.6 (65.6–85.7)

10.4 (−2.4–23.2) p = 0.11

Pain

49.0 (40.8–57.2)

58.0 (48.0–68.0)

−8.9 (−21.9–4.0) p = 0.17

39.5 (31.4–47.7)

41.4 (31.7–51.1)

−1.9 (−14.6–10.8) p = 0.77

21.3 (13.4–29.1)

30.1 (20.3–40.0)

−8.9 (−21.5–3.7) p = 0.17

17.6 (9.6–25.5)

25.2 (15.3–35.0)

−7.6 (−20.3–5.0) p = 0.24