Table 2 GRADE evidence profile
Outcomes | Certainty assessment | Effect | Certainty | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Risk of bias | Inconsistency | Indirectness | Imprecision | Others | No. of Studies | No. of Individuals | Rate (95%CI) | ||||
Cancer-related fatigue | Seriousa | Very seriousb | Not seriousc | Not seriousd | Strong associatione | 22RCTs | 1197 | SMD − 0.35 SD (− 0.63 to − 0.07) | ⨁⨁◯◯ Low | ||
Quality of life | Seriousa | Not seriousf | Not seriousc | Not seriousd | Strong associatione | 12RCTs | 590 | SMD 0.36 SD (0.20 to 0.53) | ⨁⨁⨁⨁ High | ||