Table 3 Results of two sample paired Wilcoxon sign-rank test for QST outcomes (N = 32)

Mechanical detection threshold (mN)

Control site

3.04 (0.24)

3.10 (0.35)

0.06

1.000

Pain site

3.21 (0.52)

3.24 (0.43)

0.03

0.466

Mechanical pain threshold (mN)

Control site

6.14 (0.48)

6.25 (0.44)

0.10

0.132

Pain site

6.00 (0.45)

6.13 (0.43)

0.13

0.071

Mechanical pain sensitivity (pain rating 0–10)

Control site

1.96 (1.79)

1.91 (1.67)

-0.05

0.617

Pain site

2.66 (2.11)

2.44 (1.72)

-0.22

0.439

Dynamic mechanical allodynia (pain rating 0–10)

Control site

0.76 (1.19)

0.76 (1.03)

0.11

0.452

Pain site

0.84 (1.38)

0.73 (0.97)

-0.05

0.975

Windup ratio (multiple average/single average)

Control site

2.35 (5.21)

1.57 (1.37)

-0.78

0.899

Pain site

2.57 (3.98)

2.32 (3.96)

-0.25

0.766

Vibration detection threshold (sec)

Control site

9.64 (3.13)

10.12 (3.08)

0.32

0.516

Pain site

6.71 (4.66)

7.12 (3.89)

0.43

0.765

Heat Limits (°C)

Control site

43.31 (3.67)

42.51 (3.38)

-0.80

0.651

Pain site

41.38 (3.48)

41.30 (3.10)

-0.08

0.919

Cold detection threshold (°C)

Control site

28.58 (2.22)

28.14 (2.55)

-0.44

0.304

Pain site

28.60 (1.43)

28.40 (1.12)

-0.20

0.304

Warm detection threshold (°C)

Control site

35.38 (1.37)

35.70 (1.64)

0.32

0.477

Pain site

35.82 (1.79)

36.08 (1.35)

0.26

0.029

Cold pain threshold (°C)

Control site

18.01 (9.90)

19.32 (8.12)

1.30

0.599

Pain site

18.63 (10.05)

20.24 (8.08)

1.61

0.583

Heat pain threshold (°C)

Control site

40.94 (3.83)

41.51 (3.09)

0.57

0.410

Pain site

40.65 (3.20)

40.69 (3.21)

0.03

0.978

Pressure pain threshold (kPa)

Control site

242.79 (120.25)

228.51 (140.43)

-14.28

0.239

Pain site

252.6 (128.6)

277.22 (175.06)

24.62

0.360