Table 5 Comparing mean changes in developmental and physical care burdens between four groups of caregivers

Patient-centered education

Mean

-0.61

-0.35

0.26

-0.23

0.03

0.26

SD

1.56

1.68

0.51

1.18

1.20

0.44

Caregiver-centered education

Mean

-4.48

-3.97

0.52

-1.94

-1.65

0.29

SD

2.34

2.61

0.77

1.82

2.04

0.46

Patient-caregiver education

Mean

-5.03

-4.48

0.55

-1.94

-1.58

0.35

SD

2.24

2.43

0.81

1.39

1.41

0.49

Control

Mean

0.03

0.26

0.23

0.16

0.19

0.03

SD

1.52

1.63

0.50

0.45

0.54

0.31

Comparing the four groups

F statistic

55.129

40.233

2.005

22.325

15.698

3.271

Significance level

< 0.001

< 0.001

0.117

< 0.001

< 0.001

0.024

Comparing patient-centered and caregiver-centered education

Significance level

< 0.001

< 0.001

-

< 0.001

< 0.001

0769

95% confidence interval for mean difference

2.890; 4.852

2.538; 4.687

-

1.052; 2.368

0.971; 2.383

-0.249; 0.185

Comparing patient-centered and patient and caregiver education

Significance level

< 0.001

< 0.001

-

< 0.001

< 0.001

0.379

95% confidence interval for mean difference

3.438; 5.401

3.055; 5.203

-

1.052; 2.368

0.907; 2.319

-0.314; 0.120

Comparing patient-centered education and control

Significance level

0.169

0.261

-

0.246

0.652

0.042

95% confidence interval for mean difference

-1.627; 0.336

-1.687; 0.462

-

-1.045; 0.271

-0.867; 0.545

0.009; 0.443

Comparing caregiver-centered and patient and caregiver education

Significance level

0.271

0.343

-

1.00

0.857

0.558

95% confidence interval for mean difference

-0.433; 1.530

− 0.558; 1.591

-

-0.658; 0.658

-0.770; 0.641

-0.282; 0.153

Comparing caregiver-centered education and control

Significance level

< 0.001

< 0.001

-

< 0.001

< 0.001

0.020

95% confidence interval for mean difference

-5.498; -3.535

-5.300; -3.151

-

-2.755; -1.439

-2.545; -1.133

0.041; 0.475

Comparing Patient and caregiver education and control

Significance level

< 0.001

< 0.001

-

< 0.001

< 0.001

0.004

95% confidence interval for mean difference

-6.046; -4.083

-5.816; -3.667

-

-2.755; -1.439

-2.480; -1.068

0.105; 0.540